USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: SPEE_HUMAN USC-OGP 2-DE database:  SPEE_HUMAN SPEE_HUMAN General information about the entry View entry in simple text format Entry name SPEE_HUMAN Primary accession number P19623 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Spermidine synthase; Short=SPDSY; EC=2.5.1.16; AltName: Full=Putrescine aminopropyltransferase;. Gene name Name=SRM Synonyms=SPS1, SRML1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1230: pI=5.28; Mw=34566 SPOT OGP-1235: pI=5.27; Mw=33325 Cross-references UniProtKB/Swiss-Prot P19623; SPEE_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SPEE_HUMAN Primary accession number P19623 Secondary accession number(s) B1AKP9 Q15511 Sequence was last modified on  February 1, 1991 (version 1) Annotations were last modified on  March 15, 2017 (version 178) Name and origin of the protein Description RecName: Full=Spermidine synthase; Short=SPDSY; EC=2.5.1.16; AltName: Full=Putrescine aminopropyltransferase; Gene name Name=SRM Synonyms=SPS1, SRML1 Encoded on Name=SRM; Synonyms=SPS1, SRML1 Keywords 3D-structure; Acetylation; Complete proteome; Polyamine biosynthesis; Polymorphism; Reference proteome; Spermidine biosynthesis; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M34338; AAA36633.1; -; mRNA EMBL M64231; AAA60574.1; -; Genomic_DNA EMBL AL109811; CAI22104.1; -; Genomic_DNA EMBL CH471130; EAW71675.1; -; Genomic_DNA EMBL BC000309; AAH00309.1; -; mRNA EMBL BC033106; AAH33106.1; -; mRNA CCDS CCDS125.1; -; . PIR A32610; A32610; . RefSeq NP_003123.2; NM_003132.2; . UniGene Hs.76244; -; . PDB 2O05; X-ray; 2.00 A; A/B=1-302 PDB 2O06; X-ray; 2.00 A; A/B=1-302 PDB 2O07; X-ray; 1.89 A; A/B=1-302 PDB 2O0L; X-ray; 1.99 A; A/B=1-302 PDB 3RW9; X-ray; 2.00 A; A/B=1-302 PDBsum 2O05; -; . PDBsum 2O06; -; . PDBsum 2O07; -; . PDBsum 2O0L; -; . PDBsum 3RW9; -; . ProteinModelPortal P19623; -; . SMR P19623; -; . BioGrid 112601; 20; . IntAct P19623; 7; . STRING 9606.ENSP00000366156; -; . BindingDB P19623; -; . ChEMBL CHEMBL4232; -; . DrugBank DB00118; S-Adenosylmethionine; . iPTMnet P19623; -; . PhosphoSitePlus P19623; -; . BioMuta SRM; -; . DMDM 134811; -; . EPD P19623; -; . MaxQB P19623; -; . PaxDb P19623; -; . PeptideAtlas P19623; -; . PRIDE P19623; -; . DNASU 6723; -; . Ensembl ENST00000376957; ENSP00000366156; ENSG00000116649; . GeneID 6723; -; . KEGG hsa:6723; -; . UCSC uc001arz.2; human; . CTD 6723; -; . DisGeNET 6723; -; . GeneCards SRM; -; . HGNC HGNC:11296; SRM; . HPA HPA015746; -; . MIM 182891; gene; . neXtProt NX_P19623; -; . OpenTargets ENSG00000116649; -; . PharmGKB PA36120; -; . eggNOG KOG1562; Eukaryota; . eggNOG COG0421; LUCA; . GeneTree ENSGT00870000136521; -; . HOGENOM HOG000256147; -; . HOVERGEN HBG000834; -; . InParanoid P19623; -; . KO K00797; -; . OMA LEAYCTT; -; . OrthoDB EOG091G07LZ; -; . PhylomeDB P19623; -; . TreeFam TF314466; -; . BioCyc MetaCyc:HS04027-MONOMER; -; . BRENDA 2.5.1.16; 2681; . Reactome R-HSA-351202; Metabolism of polyamines; . SABIO-RK P19623; -; . UniPathway UPA00248; UER00314; . ChiTaRS SRM; human; . EvolutionaryTrace P19623; -; . GenomeRNAi 6723; -; . PRO PR:P19623; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000116649; -; . CleanEx HS_SRM; -; . ExpressionAtlas P19623; baseline and differential; . Genevisible P19623; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0004766; F:spermidine synthase activity; IDA:UniProtKB; . GO GO:0006595; P:polyamine metabolic process; TAS:Reactome; . GO GO:0008295; P:spermidine biosynthetic process; IDA:UniProtKB; . Gene3D 3.40.50.150; -; 1; . HAMAP MF_00198; Spermidine_synth; 1; . InterPro IPR030374; PABS; . InterPro IPR030373; PABS_CS; . InterPro IPR029063; SAM-dependent_MTases; . InterPro IPR001045; Spermi_synthase; . InterPro IPR030668; Spermi_synthase_euk; . PIRSF PIRSF000502; Spermidine_synth; 1; . SUPFAM SSF53335; SSF53335; 1; . TIGRFAMs TIGR00417; speE; 1; . PROSITE PS01330; PABS_1; 1; . PROSITE PS51006; PABS_2; 1; .

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